CDC: Early Data Promising On Monkeypox Vaccine

The New York Times reports:

Americans who received a single dose of the monkeypox vaccine were significantly less likely to be infected by the virus over the summer than those who did not, according to an analysis published on Wednesday by the Centers for Disease Control and Prevention that offered a limited glimpse of the shot’s protectiveness.

The findings, gleaned from 32 states between the end of July and early September, were some of the first federal data that suggested how well the Jynneos vaccine, the main shot being used to respond to the monkeypox outbreak, prevents infections. Unvaccinated people were 14 times as likely to be infected as those who received an initial shot, the analysis found.

CNBC reports:



The data indicate that even a single dose of the vaccine provides some initial protection against infection as soon as two weeks after the shot. The Jynneos vaccine, manufactured by the Danish company Bavarian Nordic, is administered in two doses 28 days apart.

“There have been limited data on how well the Jynneos vaccine performs against monkeypox in real-world conditions,” CDC Director Rochelle Walensky said during a briefing on Wednesday. “These new data provide us with a level of cautious optimism that the vaccine is working as intended.”

But the early data has limitations. While it shows that people with one vaccine dose were infected at a lower rate than unvaccinated people, it doesn’t reflect how individuals’ behavioral changes — or other factors like testing, age or underlying health conditions — might have played into that outcome.