The ad is by Emily’s List. The Huffington Post recaps:
James Franco is back and better than ever with his second video endorsement for Democratic presidential candidate Hillary Clinton. Parodying the Dos Equis “Most Interesting Man in the World” series yet again, the actor explains why everyone should be #WithHer as pictures and clips of the former Secretary of State flash on screen. “She didn’t just bring Iran to the table, she whittled the table from a single piece of oak,” Franco coos. “Her laugh is in the Smithsonian. Yoda was her apprentice. She’s … the Most Interesting Woman in the World.”