Tag Archives: HIV vaccine

NBC News reports: The only HIV vaccine in a late-stage trial has failed, researchers announced Wednesday, dealing a significant blow to the effort to control the global HIV epidemic and adding to a decadeslong roster of failed attempts. Known as Mosaico, the trial was the product of a public-private partnership including the U.S. government and the pharmaceutical giant Janssen. It …

The Hill reports: Anthony Fauci, the nation’s top infectious diseases expert, told OZY’s Carlos Watson that the work done on COVID-19 vaccines could help develop a vaccine for HIV. “I think the success that we’ve had with developing spectacularly successful COVID-19 vaccines might help us with the breakthrough of developing an HIV vaccine,” Fauci told Watson in response to a …

From a statement by the National Institutes of Health: The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has stopped administration of vaccinations in its HVTN 702 clinical trial of an investigational HIV vaccine. This action was taken because an independent data and safety monitoring board (DSMB) found during an interim review that …

CNBC reports: Pharmaceutical giant Johnson & Johnson is set to test an experimental HIV vaccine in the U.S. and Europe sometime this year, the company confirmed with CNBC. The experimental J&J vaccine is a mosaic-based preventative immunization that targets various strains of the HIV virus. The company is also conducting a phase 2 clinical trial for the vaccine in Africa, …

Via press release from the National Institutes for Health: An experimental vaccine regimen based on the structure of a vulnerable site on HIV elicited antibodies in mice, guinea pigs and monkeys that neutralize dozens of HIV strains from around the world. The findings were reported today in the journal Nature Medicine by researchers at the National Institute of Allergy and …

Vice today released a second trailer for their coming documentary about the continuing search for an HIV vaccine and cure. Today’s trailer features legendary HIV/AIDS activist Peter Staley. The film debuts on HBO on World AIDS Day, December 1st, at 9PM.

Airing two weeks from tonight on HBO. Clip recap: Twenty years ago, HIV/AIDS was a death sentence. Now, through advances in medication, it has become a largely manageable chronic disease – and there may finally be a cure on the horizon. VICE investigates recent breakthroughs in medical science to see how close we are to life without AIDS. Hosts Shane …

God also hates African babies. Obviously.

Scientists in La Jolla, California have found a fifth area of vulnerability in HIV that may advance the search for a vaccine. The research was described in two papers published Thursday in the journal Immunity. It’s the latest product of a major effort by the National Institutes of Health and the International AIDS Vaccine Initiative, which funds work at TSRI. …

The Independent reports: A vaccine designed to tackle SIV, the monkey equivalent of HIV, may have successfully cleared the virus from infected animals, paving the way for research into a HIV vaccine for humans. It was previously thought that both the human and simian immunodeficiency viruses could be managed with antiretroviral therapies, but not eradicated. However, a study published in …

From Ontario’s Western University: Sumagen Canada Inc and Western University announced today that the Phase I Clinical Trial (SAV CT 01) of the first and only preventative HIV vaccine based on a genetically modified killed whole virus (SAV001-H) has been successfully completed with no adverse effects in all patients. Antibody production was also boosted after vaccination.  Developed by Dr. Chil-Yong …

A therapeutic HIV vaccine that temporarily “puts the brakes” on the growth of the virus has shown promise in a small study conducted by researchers in Spain. The vaccine, based on immune cells exposed to HIV that had been inactivated with heat, was tested on a group of 36 people carrying the virus and the results were the best yet …

Promising news from the University of Western Ontario. Kang said the vaccine, called SAV001, is the first preventative HIV vaccine approved for clinical trials to use a killed whole HIV-1 virus to activate the immune response in humans. The strategy has been used before to develop successful vaccines for influenza, polio, rabies and hepatitis A. Kang said these past successes …

HIV researchers at Cal Tech and UCLA report the ability to “short circuit” the immune system to block the virus. They created a disarmed adenovirus that contained the genes needed to produce a broadly effective antibody from humans, optimizing the DNA to make sure that the antibody was made in muscle cells, and then secreted into their environment. The modified …

While many who work down in the trenches of HIV/AIDS activism have long given up any hope of an effective vaccine in our lifetimes, small glimmers of hope continue to occasionally peek through the clouds. From a small vaccine study in Spain, a result that may reduce HIV to a “minor chronic infection” such as herpes: The trial demonstrated how …

More potential good news in the battle against HIV. Scientists have found a way to prevent HIV from damaging the immune system and say their discovery may offer a new approach to developing a vaccine against AIDS. Researchers from the United States and Europe working in laboratories on the human immunodeficiency virus (HIV) found it is unable to damage the …

Another advance in the search for an HIV vaccine: In a significant step toward an AIDS vaccine, U.S. government scientists have discovered three powerful antibodies, the strongest of which neutralizes 91% of HIV strains, more than any AIDS antibody yet discovered. Looking closely at the strongest antibody, they have detailed exactly what part of the virus it targets and how …

The Pharmaceutical Research and Manufacturers Association writes us today in advance of World AIDS Day (December 1st) to let us know about the 97 HIV/AIDS medications currently in the research pipeline. Conservatively, an effective HIV vaccine could prevent almost 30 million of the 150 million new infections projected in the coming decades. A highly effective vaccine could even prevent more …

The Covalent Immunology Foundation, who last week held a Manhattan event to promote their vaccine research, has rounded up some bold-face names to support their EndHIV.com site, which asks viewers for a $5 to help their cause. Actors, performers, comedians, HIV activists, and scientists come together to show support for Covalent Immunology, and Dr. Sudhir Paul. The Cast includes Lady …